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验证数据展示

  • IHC staining of mouse kidney using 16893-1-AP (same clone as 16893-1-PBS)

    IHC staining of mouse kidney using 16893-1-AP (same clone as 16893-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 16893-1-AP (TM9SF1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16893-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 16893-1-AP (same clone as 16893-1-PBS)

    IHC staining of mouse kidney using 16893-1-AP (same clone as 16893-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 16893-1-AP (TM9SF1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16893-1-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 16893-1-AP (same clone as 16893-1-PBS)

    IF Staining of U2OS using 16893-1-AP (same clone as 16893-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using TM9SF1 antibody (16893-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 16893-1-PBS in a different storage buffer formulation.

TM9SF1 Polyclonal antibody, PBS Only

TM9SF1 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 16893-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, IF/ICC, Indirect ELISA

别名

hMP70, MP70

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

16893-1-PBS targets TM9SF1 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag10418

Product name: Recombinant human TM9SF1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 30-238 aa of BC010856

Sequence: VEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 transmembrane 9 superfamily member 1
别名 hMP70, MP70
计算分子量 606 aa, 69 kDa
GenBank蛋白编号BC010856
基因名称 TM9SF1
Gene ID (NCBI) 10548
RRIDAB_3741896
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO15321
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TM9SF1, also known as HMP70 and MP70, is a membrane protein that regulates cell autophagy (PMID: 19029833). TM9SF1 deficiency inhibits the maturation of antibody-secreting plasma cells through the activation of mTOR and inhibition of autophagy. TM9SF1 is associated with the activity of autoimmune diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)(PMID: 39482663).

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