验证数据展示
产品信息
15933-1-PBS targets TIPRL in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag8780 Product name: Recombinant human TIPRL protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-178 aa of BC009506 Sequence: MMIHGFQSSHRDFCFGPWKLTASKTHIMKSADVEKLADELHMPSLPEMMFGDNVLRIQHGSGFGIEFNATDALRCVNNYQGMLKVACAEEWQESRTEGEHSKEVIKPYDWTYTTDYKGTLLGESLKLKVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIPGGGHL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | TIP41, TOR signaling pathway regulator-like (S. cerevisiae) |
| 别名 | |
| 计算分子量 | 178 aa, 20 kDa |
| 观测分子量 | 33 kDa |
| GenBank蛋白编号 | BC009506 |
| 基因名称 | TIPRL |
| Gene ID (NCBI) | 261726 |
| RRID | AB_3669227 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O75663 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TIPRL, also known as TIP, TIP4, is an inhibitory regulator of protein phosphatase-2A (PP2A) , PP4, and PP6(PMID: 17384681). TIPRL, an evolutionarily conserved protein, plays a critical role in mediating γ-H2AX signal transduction upon DNA damage(PMID: 26717153).
