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验证数据展示

  • WB analysis using 68812-3-Ig (same clone as 68812-3-PBS)

    WB analysis using 68812-3-Ig (same clone as 68812-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68812-3-Ig (THOC3 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68812-3-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 68812-3-Ig (same clone as 68812-3-PBS)

    IF Staining of A431 using 68812-3-Ig (same clone as 68812-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using THOC3 antibody (68812-3-Ig, Clone: 1A5B12 ) at dilution of 1:1000 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1), CL594-Phalloidin (red). This data was developed using the same antibody clone with 68812-3-PBS in a different storage buffer formulation.

  • IHC staining of human ovary cancer using 68812-3-Ig (same clone as 68812-3-PBS)

    IHC staining of human ovary cancer using 68812-3-Ig (same clone as 68812-3-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 68812-3-Ig (THOC3 antibody) at dilution of 1:4000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68812-3-PBS in a different storage buffer formulation.

THOC3 Monoclonal antibody, PBS Only

THOC3 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 68812-3-PBS

产品说明书

CloneNo. 1A5B12

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

hTREX45, TEX1, Tho3

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

68812-3-PBS targets THOC3 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag35578

Product name: Recombinant human THOC3 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-348 aa of BC006849

Sequence: MAVPAAAMGPSALGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCESPTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLFGLP

种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 THO complex 3
别名 hTREX45, TEX1, Tho3
计算分子量 327 aa, 36 kDa
观测分子量39 kDa
GenBank蛋白编号BC006849
基因名称 THOC3
Gene ID (NCBI) 84321
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ96J01
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

THOC3 is a component of the nuclear THO transcription elongation complex, which is a part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. Additionally, THOC3 plays a key role in many cellular mechanisms, such as in the pathogenesis of cancer and neurodegenerative diseases (PMID: 36674977). THOC3 has 2 isoforms with the molecular weights of 36 kDa and 39 kDa.

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