验证数据展示
产品信息
68923-1-PBS targets THEM4 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag6296 Product name: Recombinant human THEM4 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-240 aa of BC065277 Sequence: MLRSCAARLRTLGALCRPPVGRRLPGSEPRPELRSFSSEEVILKDCSVPNPSWNKDLRLLFDQFMKKCEDGSWKRLPSYKRTPTEWIQDFKTHFLDPKLMKEEQMSQAQLFTRSFDDGLGFEYVMFYNDIEKRMVCLFQGGPYLEGPPGFIHGGAIATMIDATVGMCAMMAGGIVMTANLNINYKRPIPLCSVVMINSQLDKVEGRKFFVSCNVQSVDEKTLYSEATSLFIKLNPAKSLT 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | thioesterase superfamily member 4 |
| 别名 | CTMP, EC:3.1.2.2, Carboxyl-terminal modulator protein, Acyl-coenzyme A thioesterase THEM4, Acyl-CoA thioesterase THEM4 |
| 计算分子量 | 27 kDa |
| 观测分子量 | 26 kDa |
| GenBank蛋白编号 | BC065277 |
| 基因名称 | CTMP |
| Gene ID (NCBI) | 117145 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q5T1C6 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
THEM4, which stands for thioesterase superfamily member 4, is a gene in humans that encodes a protein involved in the regulation of the protein kinase B (PKB), also known as Akt pathway. This gene is ubiquitously expressed in various tissues, with notable expression in the kidney and testis. THEM4 can also promote the proliferation of tumor cells by positively regulating Akt activity in breast cancer and nasopharyngeal carcinoma, which presents a contrasting role to its initial characterization.