TGFBI/BIGH3 Recombinant antibody

TGFBI/BIGH3 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 80805-4-RR

产品说明书

CloneNo. 243108F7

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

TGFBI, TGFBI / BIGH3, Beta ig h3, Beta ig-h3, BIGH3

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存


经过测试的应用

Positive WB detected inHeLa cells, A549 cells
Planning an IHC experiment? We recommend our IHCeasy TGFBI Ready-To-Use IHC Kit. TGFBI primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

80805-4-RR targets TGFBI/BIGH3 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 TGFBI/BIGH3 fusion protein Eg1233 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 transforming growth factor, beta-induced, 68kDa
别名 TGFBI, TGFBI / BIGH3, Beta ig h3, Beta ig-h3, BIGH3
计算分子量75kDa
观测分子量68 kDa
GenBank蛋白编号NM_000358.3
基因名称 TGFBI
Gene ID (NCBI) 7045
ENSEMBL Gene IDENSG00000120708
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ15582
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TGFBI, also named as BIGH3, Kerato-epithelin and RGD-CAP, binds to type I, II, and IV collagens. TGFBI is an adhesion protein which may play an important role in cell-collagen interactions. In cartilage, it may be involved in endochondral bone formation. TGFBI is an extracellular matrix adaptor protein, it has been reported to be differentially expressed in transformed tissues. TGFBI is a predictive factor of the response to chemotherapy, and suggest the use of TGFBI-derived peptides as possible therapeutic adjuvants for the enhancement of responses to chemotherapy.(PMID:20509890) Defects in TGFBI are the cause of epithelial basement membrane corneal dystrophy (EBMD). Defects in TGFBI are the cause of corneal dystrophy Groenouw type 1 (CDGG1). Defects in TGFBI are the cause of corneal dystrophy lattice type 1 (CDL1). Defects in TGFBI are a cause of corneal dystrophy Thiel-Behnke type (CDTB). Defects in TGFBI are the cause of Reis-Buecklers corneal dystrophy (CDRB). Defects in TGFBI are the cause of lattice corneal dystrophy type 3A (CDL3A). Defects in TGFBI are the cause of Avellino corneal dystrophy (ACD).

实验方案

Product Specific Protocols
WB protocol for TGFBI/BIGH3 antibody 80805-4-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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