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验证数据展示

  • WB analysis of HEK-293 using 14595-1-AP (same clone as 14595-1-PBS)

    WB analysis of HEK-293 using 14595-1-AP (same clone as 14595-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 14595-1-AP (TERF2IP antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14595-1-PBS in a different storage buffer formulation.

  • IP experiment of HeLa using 14595-1-AP (same clone as 14595-1-PBS)

    IP experiment of HeLa using 14595-1-AP (same clone as 14595-1-PBS)

    IP result of anti-TERF2IP (IP:14595-1-AP, 3ug; Detection:14595-1-AP 1:800) with HeLa cells lysate 2720ug. This data was developed using the same antibody clone with 14595-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 14595-1-AP (same clone as 14595-1-PBS)

    IHC staining of human tonsillitis using 14595-1-AP (same clone as 14595-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 14595-1-AP (TERF2IP antibody) at dilution of 1:2000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14595-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TERF2IP antibody included
  • IF Staining of HeLa using 14595-1-AP (same clone as 14595-1-PBS)

    IF Staining of HeLa using 14595-1-AP (same clone as 14595-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using TERF2IP antibody (14595-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 14595-1-PBS in a different storage buffer formulation.

TERF2IP Polyclonal antibody, PBS Only

TERF2IP Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 14595-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

Telomeric repeat-binding factor 2-interacting protein 1, RAP1 homolog, PP8000, hRap1, DRIP5

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy TERF2IP Ready-To-Use IHC Kit. TERF2IP primary antibody included.

产品信息

14595-1-PBS targets TERF2IP in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag6130

Product name: Recombinant human TERF2IP protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-268 aa of BC005841

Sequence: MAEAMDLGKDPNGPTHSSTLFVRDDGSSMSFYVRPSPAKRRLSTLILHGGGTVCRVQEPGAVLLAQPGEALAEASGDFISTQYILDCVERNERLELEAYRLGPASAADTGSEAKPGALAEGAAEPEPQRHAGRIAFTDADDVAILTYVKENARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 telomeric repeat binding factor 2, interacting protein
别名 Telomeric repeat-binding factor 2-interacting protein 1, RAP1 homolog, PP8000, hRap1, DRIP5
计算分子量 44 kDa
观测分子量 60 kDa
GenBank蛋白编号BC005841
基因名称 TERF2IP
Gene ID (NCBI) 54386
RRIDAB_10642697
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NYB0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TERF2IP, also named as DRIP5, RAP1, is a 399 amino acid protein, which belongs to the RAP1 family. TERF2IP associates with chromosomes, both at telomeres and in extratelomeric sites. TERF2IP acts both as a regulator of telomere function and as a transcription regulator. TERF2IP is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. The calculated molecular weight of TERF2IP is 44 kDa, but modified TERF2IP, is about 60 kDa. (PMID: 15838871)

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