验证数据展示
产品信息
26994-1-PBS targets TCTEX1D2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag25770 Product name: Recombinant human TCTEX1D2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-142 aa of BC021177 Sequence: MATSIGVSFSVGDGVPEAEKNAGEPENTYILRPVFQQRFRPSVVKDCIHAVLKEGLANAEYSPEEMPQLTKHLSENIKDKLKEMGFDRYKMVVQVVIGEQRGEGVFMASRCFWDADTDNYTHDVFMNDSLFCVVAAFGCFYY 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | Tctex1 domain containing 2 |
| 别名 | DYNLT2B |
| 观测分子量 | 16 kDa |
| GenBank蛋白编号 | BC021177 |
| 基因名称 | TCTEX1D2 |
| Gene ID (NCBI) | 255758 |
| RRID | AB_2890214 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8WW35 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
DYNLT2B also known as TCTEX1D2, belongs to the dynein family and is required for proper retrograde ciliary transport(PMID: 29742051). TCTEX1D2 functions as a light chain that appears to stabilize the retrograde IFT dynein complex. Mutations in TCTEX1D2 are associated with Short-rib thoracic dysplasia 17 with or without polydactyly (SRTD17)( PMID: 26044572).
