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验证数据展示

  • WB analysis using 14424-1-AP (same clone as 14424-1-PBS)

    WB analysis using 14424-1-AP (same clone as 14424-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14424-1-AP (TAX1BP1 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14424-1-PBS in a different storage buffer formulation.

  • IHC staining of human skin cancer using 14424-1-AP (same clone as 14424-1-PBS)

    IHC staining of human skin cancer using 14424-1-AP (same clone as 14424-1-PBS)

    Immunohistochemical analysis of paraffin-embedded skin cancer slide using 14424-1-AP (TAX1BP1 antibody) at dilution of 1:500 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14424-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 14424-1-AP (same clone as 14424-1-PBS)

    IF Staining of HeLa using 14424-1-AP (same clone as 14424-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using TAX1BP1 antibody (14424-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 14424-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

TAX1BP1 Polyclonal antibody, PBS Only

TAX1BP1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 14424-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

14424-1-PBS targets TAX1BP1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag5789

Product name: Recombinant human TAX1BP1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 454-789 aa of BC050358

Sequence: KECQRLQKQINKLSDQSANNNNVFTKKTGNQQKVNDASVNTDPATSASTVDVKPSPSAAEADFDIVTKGQVCEMTKEIADKTEKYNKCKQLLQDEKAKCNKYADELAKMELKWKEQVKIAENVKLELAEVQDNYKELKRSLENPAERKMEGQNSQSPQCFKTCSEQNGYVLTLSNAQPVLQYGNPYASQETRDGADGAFYPDEIQRPPVRVPSWGLEDNVVCSQPARNFSRPDGLEDSEDSKEDENVPTAPDPPSQHLRGHGTGFCFDSSFDVHKKCPLCELMFPPNYDQSKFEEHVESHWKVCPMCSEQFPPDYDQQVFERHVQTHFDQNVLNFD

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 Tax1 (human T-cell leukemia virus type I) binding protein 1
别名 TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105
计算分子量 91 kDa
观测分子量 90 kDa
GenBank蛋白编号BC050358
基因名称 TAX1BP1
Gene ID (NCBI) 8887
RRIDAB_2198921
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ86VP1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5.

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