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验证数据展示

  • WB analysis using 10161-1-AP (same clone as 10161-1-PBS)

    WB analysis using 10161-1-AP (same clone as 10161-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 10161-1-AP (TAP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10161-1-PBS in a different storage buffer formulation.

  • IHC staining of human intrahepatic cholangiocarcinoma using 10161-1-AP (same clone as 10161-1-PBS)

    IHC staining of human intrahepatic cholangiocarcinoma using 10161-1-AP (same clone as 10161-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 10161-1-AP (TAP2 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10161-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TAP2 antibody included
  • IHC staining of human ovary cancer using 10161-1-AP (same clone as 10161-1-PBS)

    IHC staining of human ovary cancer using 10161-1-AP (same clone as 10161-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 10161-1-AP (TAP2 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10161-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with TAP2 antibody included

TAP2 Polyclonal antibody, PBS Only

TAP2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 10161-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

PSF-2, PSF2, EC:7.4.2.14, ATP-binding cassette sub-family B member 3, APT2

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy TAP2 Ready-To-Use IHC Kit. TAP2 primary antibody included.

产品信息

10161-1-PBS targets TAP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag0190

Product name: Recombinant human TAP2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-223 aa of BC002751

Sequence: MRLPDLRPWTSLLLVDAALLWLLQGPLGTLLPQGLPGLWLEGTLRLGGLWGLLKLRGLLGFVGTLLLPLCLATPLTVSLRALVAGASRAPPARVASAPWSWLLVGYGAAGLSWSLWAVLSPPGAQEKEQDQVNNKVLMWRLLKLSRPDLPLLVAAFFFLVLAVLGETLIPHYSGRVIDILGGDFDPHAFASAIFFMCLFSFGSSLSAGCRGGCFTYTMSRINL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
别名 PSF-2, PSF2, EC:7.4.2.14, ATP-binding cassette sub-family B member 3, APT2
计算分子量 76 kDa
观测分子量70 kDa
GenBank蛋白编号BC002751
基因名称 TAP2
Gene ID (NCBI) 6891
RRIDAB_3085365
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ03519
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TAP2, also known as APT2, ABCB3, is a member of the superfamily of ATP-binding cassette (ABC) transporters. TAP2 mediates unidirectional translocation of peptide antigens from cytosol to endoplasmic reticulum (ER) for loading onto MHC class I (MHCI) molecules (PMID: 25656091). Mutations in TAP2 may be associated with Bare lymphocyte syndrome 1 (BLS1) and schizophrenia(PMID: 7517574, 24365204).

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