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验证数据展示

  • WB analysis using 12642-1-AP (same clone as 12642-1-PBS)

    WB analysis using 12642-1-AP (same clone as 12642-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12642-1-AP (Synaptotagmin-4 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12642-1-PBS in a different storage buffer formulation.

  • IHC staining of human gliomas using 12642-1-AP (same clone as 12642-1-PBS)

    IHC staining of human gliomas using 12642-1-AP (same clone as 12642-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas using 12642-1-AP (Synaptotagmin-4 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 12642-1-PBS in a different storage buffer formulation.

Synaptotagmin-4 Polyclonal antibody, PBS Only

Synaptotagmin-4 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 12642-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

KIAA1342, Synaptotagmin IV, SYT4, SytIV

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

12642-1-PBS targets Synaptotagmin-4 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag3338

Product name: Recombinant human SYT4 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 86-425 aa of BC036538

Sequence: AVPKNSLHLDLEKRDLNGNFPKTNLKPGSPSDLENATPKLFLEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVLCDG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 synaptotagmin IV
别名 KIAA1342, Synaptotagmin IV, SYT4, SytIV
计算分子量 425 aa, 48 kDa
观测分子量 45-48 kDa
GenBank蛋白编号BC036538
基因名称 Synaptotagmin-4
Gene ID (NCBI) 6860
RRIDAB_2302982
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H2B2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (PMID: 8058779). Synaptotagmin-4 is an atypical synaptic vesicle protein that is expressed in the dendrites of neurons. It mediates retrograde signals at the synapse and the release of BDNF, and regulates synaptic plasticity, motor learning, and memory. (PMID: 27223326;29166604 )

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