验证数据展示
产品信息
20663-1-PBS targets Stabilin-1 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | IHC, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | stabilin 1 |
| 别名 | STAB1, CLEVER 1, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1, FEEL 1, FEEL1 |
| 计算分子量 | 276 kDa |
| GenBank蛋白编号 | NM_015136 |
| 基因名称 | STAB1 |
| Gene ID (NCBI) | 23166 |
| RRID | AB_2878721 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9NY15 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Stabilin-1, also known as FEEL-1 or CLEVER-1, is a large type I transmembrane scavenger receptor primarily expressed on tissue-resident macrophages and lymphatic sinus endothelial cells. It functions in endocytosis, intracellular sorting, phagocytosis, and cell adhesion, and is highly upregulated in alternatively activated macrophages by IL-4 and dexamethasone. The protein localizes to endosomes and the trans-Golgi network, playing essential roles in immune regulation, pathogen clearance, and tissue homeostasis. (PMID: 16989725)




