• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 85938-2-RR (same clone as 85938-2-PBS)

    WB analysis using 85938-2-RR (same clone as 85938-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85938-2-RR (Spartin/SPG20 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85938-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85938-2-RR

    Affinity and Kinetic Characterization of 85938-2-RR

    Biolayer interferometry (BLl) kinetic assays of 85938-2-RR against Human Spartin/SPG20 were performed. The affinity constant is 1.66 nM.

Spartin/SPG20 Recombinant antibody, PBS Only

Spartin/SPG20 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85938-2-PBS

产品说明书

CloneNo. 250440A11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

SPG20, KIAA0610, SPART, Spartin, SPG 20

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

85938-2-PBS targets Spartin/SPG20 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Spartin/SPG20 fusion protein Ag4815 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 spastic paraplegia 20 (Troyer syndrome)
别名 SPG20, KIAA0610, SPART, Spartin, SPG 20
计算分子量 72 kDa
观测分子量 75-84 kDa
GenBank蛋白编号BC047083
基因名称 Spartin
Gene ID (NCBI) 23111
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ8N0X7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SPG20 (spastic paraplegia 20) gene encodes a multifunctional Spartin protein. SPG20 protein is highly expressed in adipose tissue and may be implicated in endosomal trafficking and microtubule dynamics. SPG20 is mutated in Troyer syndrome, a hereditary spastic paraplegia defined by degeneration of upper motor neurons, recent study showed that regulation of SPG20 on mitochondrial calcium homeostasis may contribute to the pathophysiology of Troyer syndrome. Hypermethylation of SPG20 promoter, found in colorectal cancer patients, may play a role in cytokinesis arrest in colorectal tumorigenesis.