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验证数据展示

  • WB analysis using 84161-3-RR (same clone as 84161-3-PBS)

    WB analysis using 84161-3-RR (same clone as 84161-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84161-3-RR (SYNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84161-3-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 84161-3-RR (same clone as 84161-3-PBS)

    IF Staining of mouse brain using 84161-3-RR (same clone as 84161-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using SYNGR1 antibody (84161-3-RR, Clone: 241460D1 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84161-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84161-3-RR

    Affinity and Kinetic Characterization of 84161-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84161-3-RR against Human SYNGR1 were performed. The affinity constant is 3.48 nM.

SYNGR1 Recombinant monoclonal antibody, PBS Only

SYNGR1 Uni-rAb® Recombinant Antibody for WB, IF-P, Indirect ELISA
Cat No. 84161-3-PBS

产品说明书

CloneNo. 241460D1

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat, pig

应用

WB, IF-P, Indirect ELISA

别名

Synaptogyrin-1, synaptogyrin 1, 241460D1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

84161-3-PBS targets SYNGR1 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat, pig
免疫原

CatNo: Ag0685

Product name: Recombinant human SYNGR1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-191 aa of BC000731

Sequence: MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFKDLSFQEEYSTLFPASAQP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 synaptogyrin 1
别名 Synaptogyrin-1, synaptogyrin 1, 241460D1
计算分子量 25 kDa
观测分子量30 kDa
GenBank蛋白编号BC000731
基因名称 SYNGR1
Gene ID (NCBI) 9145
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDO43759
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Synaptogyrins are one of the most abundant vesicle components and are involved in the regulation of neurotransmitter release and synaptic plasticity. Synaptogyrins comprise a family of tyrosine-phosphorylated proteins with three isoforms: two neuronal forms (synaptogyrin-1 and -3) and one ubiquitous form (synaptogyrin-2). The synaptogyrin 1 (SYNGR1) can act as a regulator of Ca2+-dependent exocytosis. SYNGR1 protein mutations are associated with schizophrenia and are considered to be positional candidate genes for schizophrenia.(PMID: 10383386; 10595519; 14755516; 14732601; 17049558)

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