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验证数据展示

  • WB analysis using 13599-1-AP (same clone as 13599-1-PBS)

    WB analysis using 13599-1-AP (same clone as 13599-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13599-1-AP (SUR2/ABCC9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13599-1-PBS in a different storage buffer formulation.

  • WB analysis using 13599-1-AP (same clone as 13599-1-PBS)

    WB analysis using 13599-1-AP (same clone as 13599-1-PBS)

    mouse heart were subjected to SDS PAGE followed by western blot with 13599-1-AP (SUR2/ABCC9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13599-1-PBS in a different storage buffer formulation.

SUR2/ABCC9 Polyclonal antibody, PBS Only

SUR2/ABCC9 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 13599-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

13599-1-PBS targets SUR2/ABCC9 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag4536

Product name: Recombinant human ABCC9 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-149 aa of BC033804

Sequence: MSLSFCGNNISSYNINDGVLQNSCFVDALNLVPHVFLLFITFPILFIGWGSQSSKVQIHHNTWLHFPGHNLRWILTFALLFVHVCEIAEGIVSDSRRESRHLHLFMPAVMGFVATTTSIVYYHNIETSNFPKLLLGFSHHESKSCYQHS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
别名
计算分子量 1549 aa, 174 kDa
观测分子量174 kDa
GenBank蛋白编号BC033804
基因名称 SUR2/ABCC9
Gene ID (NCBI) 10060
RRIDAB_3085419
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO60706
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ABCC9, also known as SUR2, belongs to the ABC transporter superfamily. ABCC9 is a subunit of ATP-sensitive potassium channels (KATP), forming cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (PMID: 9831708). ABCC9 is thought to form ATP-sensitive potassium channels in cardiac, skeletal, vascular, and non-vascular smooth muscle. Defects in ABCC9 cause dilated cardiomyopathy 10 and familial atrial fibrillation type 12 (ATFB12)(PMID: 15034580,17245405).

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