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验证数据展示

  • IHC staining of mouse kidney using 31987-1-AP

    IHC staining of mouse kidney using 31987-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31987-1-AP (SUCNR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of mouse liver using 31987-1-AP

    IHC staining of mouse liver using 31987-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 31987-1-AP (SUCNR1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

SUCNR1 Polyclonal antibody

SUCNR1 Polyclonal Antibody for IHC, ELISA
Cat No. 31987-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, ELISA

别名

Succinate receptor 1, P2Y purinoceptor 1-like, P2Y purinoceptor 1 like, G-protein coupled receptor 91, GPR91

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive IHC detected inmouse kidney tissue, mouse liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

31987-1-AP targets SUCNR1 in IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human, mouse
免疫原 SUCNR1 fusion protein Ag34053 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 succinate receptor 1
别名 Succinate receptor 1, P2Y purinoceptor 1-like, P2Y purinoceptor 1 like, G-protein coupled receptor 91, GPR91
GenBank蛋白编号BC030948
基因名称 SUCNR1
Gene ID (NCBI) 56670
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ9BXA5
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SUCNR1 (Succinate Receptor 1), also known as GPR91, belongs to the family of G protein-coupled receptors (GPCRs) (PMID: 26808164). SUCNR1 has been identified as a receptor for the metabolite succinate, which functions as a metabolic stress signal in various tissues including the liver, kidney, adipose tissue, and retina (PMID: 29968758). SUCNR1 is crucial in linking metabolic stress, inflammation, and energy homeostasis. It mediates signaling through Gq/GNAQ or Gi/GNAI second messengers depending on the cell type and regulated processes.

实验方案

Product Specific Protocols
IHC protocol for SUCNR1 antibody 31987-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols