验证数据展示
经过测试的应用
| Positive WB detected in | HEK-293T cells, HeLa cells, Jurkat cells, RT-4 cells, U-251 cells, NIH/3T3 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:6000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
34199-1-AP targets STRN4 in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag38564 Product name: Recombinant human STRN4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 200-350 aa of NM_013403.2 Sequence: RSLLGRSLELNGAVEPSEGAPRAPPGPAGLSGGESLLVKQIEEQIKRNAAGKDGKERLGGSVLGQIPFLQNCEDEDSDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFDFLGSGEDGEGAPDPRRCTVDGSPHELESRR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | striatin, calmodulin binding protein 4 |
| 别名 | Striatin-4, ZIN, Zinedin |
| 计算分子量 | 81kDa，753aa |
| 观测分子量 | 90 kDa |
| GenBank蛋白编号 | NM_013403.2 |
| 基因名称 | STRN4 |
| Gene ID (NCBI) | 29888 |
| RRID | AB_3743170 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q9NRL3 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
STRN4, or Striatin 4, is a scaffold protein essential for organizing protein complexes within cells. It is conserved across many species, including humans, mice, and rats, and plays a critical role in cellular signaling, particularly in neurons. STRN4 is a core component of the STRIPAK complex (Striatin-Interacting Phosphatase and Kinase complex). This complex integrates signals from kinases and phosphatases to control fundamental processes like cell growth, differentiation, and neuronal development.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for STRN4 antibody 34199-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
