STRA6 Polyclonal antibody

STRA6 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB, ELISA and More (2)

Conjugate

Unconjugated

Cat No : 22001-1-AP

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Synonyms

MCOPS9, PP14296, STRA6, UNQ3126/PRO10282/PRO19578



经过测试的应用

Positive WB detected inmouse kidney tissue, rat kidney tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

22001-1-AP targets STRA6 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA
Cited ApplicationsWB, IF, IHC
Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, rat
Immunogen STRA6 fusion protein Ag17591 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name stimulated by retinoic acid gene 6 homolog (mouse)
Synonyms MCOPS9, PP14296, STRA6, UNQ3126/PRO10282/PRO19578
Calculated Molecular Weight 667 aa, 74 kDa
Observed Molecular Weight 73-78 kDa
GenBank Accession NumberBC025256
Gene Symbol STRA6
Gene ID (NCBI) 64220
RRIDAB_11064606
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9BX79
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

STRA6, also known as MCOPS9 and PP14296. Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin. (PMID:9452451; 18316031; 22665496; 21368206; 22665496).

实验方案

Product Specific Protocols
WB protocol for STRA6 antibody 22001-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseIF,WB

Int J Mol Sci

Retinoid Regulation of Ocular Surface Innate Inflammation.

Authors - Jehan Alam
humanIF

Sci Rep

TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.

Authors - S Prpar Mihevc
humanIF

Endocrinology

De novo-synthesized retinoic acid in ovarian antral follicles enhances FSH-mediated ovarian follicular cell differentiation and female fertility.

Authors - Tomoko Kawai
mouseIHC

Lab Invest

Nuclear receptor binding factor 2 (NRBF2) is required for learning and memory.

Authors - Xiaosen Ouyang
ratWB

eNeuro

Differential Retinoic Acid Signaling in the Hippocampus of Aged Rats with and without Memory Impairment.

Authors - Marta U Wołoszynowska-Fraser
mouseWB

J Food Biochem

Inhibitory effect of chitooligosaccharides on retinol metabolism and bioavailability in mice.

Authors - Wei Li