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STARD7 Polyclonal antibody

STARD7 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 15689-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA

START domain-containing protein 7, StAR-related lipid transfer protein 7, mitochondrial, GTT1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存


经过测试的应用

Positive WB detected inHeLa cells, HepG2 cells, K-562 cells, mouse testis tissue
Positive IHC detected inhuman colon cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:8000
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

15689-1-AP targets STARD7 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB
经测试反应性 human, mouse, rat
文献引用反应性human, mouse
免疫原

CatNo: Ag8224

Product name: Recombinant human STARD7 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-295 aa of BC008894

Sequence: MAALAGVFVWDEERIQEEELQRSINEMKRLEEMSNMFQSSGVQHHPPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAKATSQSSERKNEGSCGPARIEYA

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 StAR-related lipid transfer (START) domain containing 7
别名 START domain-containing protein 7, StAR-related lipid transfer protein 7, mitochondrial, GTT1
计算分子量 295 aa, 35 kDa
观测分子量 34 kDa
GenBank蛋白编号BC008894
基因名称 STARD7
Gene ID (NCBI) 56910
RRIDAB_2197820
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NQZ5
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

STARD7, also known as gestational trophoblastic tumor gene-1 (GTT1), is a lipid transfer protein that specifically binds and transports phosphatidylcholine (PC) between cellular membranes. It is a member of the START (Steroidogenic Acute Regulatory protein-related lipid transfer) domain-containing protein family, which is involved in intracellular lipid transport and metabolism. (PMID: 23507753)

实验方案

Product Specific Protocols
WB protocol for STARD7 antibody 15689-1-APDownload protocol
IHC protocol for STARD7 antibody 15689-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Nat Cell Biol

PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.

Authors - Shotaro Saita
humanWB

Nat Commun

Intronic ATTTC repeat expansions in STARD7 in familial adult myoclonic epilepsy linked to chromosome 2.

Authors - Mark A Corbett
humanWB

EMBO J

PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.

Authors - Shotaro Saita
mouseWB

EMBO Mol Med

Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.

Authors - Hans-Georg Sprenger
humanWB

J Lipid Res

A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7.

Authors - Svenja Bockelmann
  • KO Validated
humanWB

iScience

Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway

Authors - Neeraja Purandare
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