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验证数据展示

  • WB analysis using 87115-2-RR

    WB analysis using 87115-2-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 87115-2-RR (STAC2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

  • Affinity of 87115-2-RR

    Affinity of 87115-2-RR

    Biolayer interferometry (BLl) kinetic assays of 87115-2-RR against Human STAC2 were performed. The affinity constant is 7.03 nM.

STAC2 Recombinant monoclonal antibody

STAC2 Uni-rAb® Recombinant Antibody for WB, ELISA
Cat No. 87115-2-RR

产品说明书

CloneNo. 251759B12

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

24b2, 24b2/STAC2, SH3 and cysteine rich domain 2, SH3 and cysteine-rich domain-containing protein 2, Src homology 3 and cysteine-rich domain-containing protein 2

缓冲液配方:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inSH-SY5Y cells, K-562 cells, THP-1 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

87115-2-RR targets STAC2 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag16601

Product name: Recombinant human STAC2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 65-154 aa of BC109231

Sequence: TLRYGTSLALMNRSSFSSTSESPTRSLSERDELTEDGEGSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 SH3 and cysteine rich domain 2
别名 24b2, 24b2/STAC2, SH3 and cysteine rich domain 2, SH3 and cysteine-rich domain-containing protein 2, Src homology 3 and cysteine-rich domain-containing protein 2
计算分子量 411 aa, 45 kDa
观测分子量55-57 kDa
GenBank蛋白编号BC109231
基因名称 STAC2
Gene ID (NCBI) 342667
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ6ZMT1
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

STAC2 (Src homology 3 and cysteine-rich domain 2) contains an SH3 domain and a zinc finger domain. STAC2 has been shown to negatively regulate osteoclast formation by targeting the RANK signaling complex. This mechanism involves inhibiting the formation of complexes containing Gab2 and PLCγ2, thereby suppressing NF-κB and MAPK signaling pathways.

实验方案

Product Specific Protocols
WB protocol for STAC2 antibody 87115-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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