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Host
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0
Conjugate
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验证数据展示

  • WB analysis using 87663-1-RR (same clone as 87663-1-PBS)

    WB analysis using 87663-1-RR (same clone as 87663-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 87663-1-RR (SSTR2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87663-1-PBS in a different storage buffer formulation.

  • WB analysis of SH-SY5Y using 87663-1-RR (same clone as 87663-1-PBS)

    WB analysis of SH-SY5Y using 87663-1-RR (same clone as 87663-1-PBS)

    WB result of SSTR2 antibody (87663-1-RR; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SSTR2 transfected SH-SY5Y cells. This data was developed using the same antibody clone with 87663-1-PBS in a different storage buffer formulation.

  • Affinity of 87663-1-RR

    Affinity of 87663-1-RR

    Biolayer interferometry (BLl) kinetic assays of 87663-1-RR against Human SSTR2 were performed. The affinity constant is 0.529 nM.

SSTR2 Recombinant monoclonal antibody, PBS Only

SSTR2 Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 87663-1-PBS

产品说明书

CloneNo. 251649C10

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

somatostatin receptor 2, Somatostatin receptor type 2, SRIF 1, SRIF-1, SS 2 R

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

87663-1-PBS targets SSTR2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag14205

Product name: Recombinant human SSTR2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-60 aa of BC019610

Sequence: MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 somatostatin receptor 2
别名 somatostatin receptor 2, Somatostatin receptor type 2, SRIF 1, SRIF-1, SS 2 R
计算分子量 369 aa, 41 kDa
观测分子量85 kDa
GenBank蛋白编号BC019610
基因名称 SSTR2
Gene ID (NCBI) 6752
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP30874
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Somatostatin receptor 2 (SSTR2) is a G-protein coupled membrane receptor expressed in a variety of neural and neurosecretory tissue types. In neuroendocrine tumors (NETs), in which Somatostatin receptors (SSTRs) are commonly expressed, the detection of SSTR2 expression has both diagnostic and therapeutic potential. Besides NETs, SSTR2 immunostaining can be detected in other types of tumor cells(PMID:34786053). Moreover, SSTR2 is consistently expressed in Olfactory neuroblastoma (ONB) suggesting a role for somatostatin-analog based imaging and therapy in this disease. More generally, SSTR2 may be another marker of neuroendocrine diferentiation in ONB(PMID:33929681).

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