验证数据展示
经过测试的应用
| Positive WB detected in | pig cerebellum tissue, mouse brain tissue, pig brain tissue, rat brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
60681-2-Ig targets SSTR1 in WB, ELISA applications and shows reactivity with human, mouse, rat, pig samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat, pig |
| 免疫原 |
CatNo: Ag30826 Product name: Recombinant human SSTR1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 328-391 aa of BC035618 Sequence: DNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | somatostatin receptor 1 |
| 别名 | somatostatin receptor 1, Somatostatin receptor type 1, SRIF 2, SRIF-2, SS 1 R |
| 计算分子量 | 391 aa, 43 kDa |
| 观测分子量 | 53 kDa |
| GenBank蛋白编号 | BC035618 |
| 基因名称 | SSTR1 |
| Gene ID (NCBI) | 6751 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P30872 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SSTR1 is a Gi/o-coupled somatostatin receptor expressed in the brain, pancreas, and gastrointestinal epithelium, where it modulates neurotransmission, hormone secretion, and cellular proliferation. Through suppression of cAMP and regulation of Ca²⁺ signaling, SSTR1 mediates key inhibitory actions of somatostatin. Its expression in neuroendocrine tumors and roles in metabolic and neurological regulation underscore its clinical and biological relevance.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for SSTR1 antibody 60681-2-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
