验证数据展示
Planning an IHC experiment? We recommend our IHCeasy SRGAP1 Ready-To-Use IHC Kit. SRGAP1 primary antibody included.
产品信息
20222-1-AP targets SRGAP1-Specific in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | SLIT-ROBO Rho GTPase activating protein 1 |
| 别名 | ARHGAP13, KIAA1304, SRGAP1 |
| 计算分子量 | 124 kDa |
| GenBank蛋白编号 | NM_020762 |
| 基因名称 | SRGAP1 |
| Gene ID (NCBI) | 57522 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q7Z6B7 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SRGAP1, also named as ARHGAP13 and KIAA1304, is a GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42, SRGAP1 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. This antibody is specific to SRGAP1. It can’t recognize SRGAP2 and SRGAP3.