验证数据展示
产品信息
11350-1-PBS targets SRCRB4D in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag1884 Product name: Recombinant human SRCRB4D protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-190 aa of BC015651 Sequence: MTGTLRTRAWPAAKRAAGLRWALRDEARLSDCFHLGWGQHNCGHHEDAGALCAGEADSEGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | scavenger receptor cysteine rich domain containing, group B (4 domains) |
| 别名 | Four scavenger receptor cysteine-rich domains-containing protein, S4D-SRCRB, Scavenger receptor cysteine-rich domain-containing group B protein, SSC4D |
| 计算分子量 | 61 kDa |
| 观测分子量 | 70 kDa |
| GenBank蛋白编号 | BC015651 |
| 基因名称 | SRCRB4D |
| Gene ID (NCBI) | 136853 |
| RRID | AB_3741817 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8WTU2 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SRCRB4D (also known as SSC4D or S4D-SRCRB) is a soluble, secreted pattern-recognition receptor belonging to the scavenger receptor cysteine-rich (SRCR) superfamily, characterized by four group B SRCR domains. It is broadly expressed in epithelial cells of the kidney, placenta, liver, intestine, and lung, and functions as an innate immune sensor capable of binding diverse bacteria and protozoan parasites, thereby enhancing phagocytosis by monocytes.
