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SPTBN2 Polyclonal antibody

SPTBN2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, ELISA and More (1)

Conjugate

Unconjugated

Cat No : 55107-1-AP

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Synonyms

Beta III spectrin, SCA5, Spectrin beta chain, brain 2, Spectrin beta-3, SPTBN2



经过测试的应用

Positive WB detected inHeLa cells, human brain tissue, mouse brain, rat brain

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

55107-1-AP targets SPTBN2 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA
Cited ApplicationsWB, IF
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, Drosophila
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name spectrin, beta, non-erythrocytic 2
Synonyms Beta III spectrin, SCA5, Spectrin beta chain, brain 2, Spectrin beta-3, SPTBN2
Calculated Molecular Weight 271 kDa
Observed Molecular Weight 270 kDa
GenBank Accession NumberNM_006946
Gene Symbol SPTBN2
Gene ID (NCBI) 6712
RRIDAB_10804779
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO15020
Storage Buffer 0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SPTBN2, also named as KIAA0302, belongs to the spectrin family. It probably plays an important role in neuronal membrane skeleton. Defects in SPTBN2 are the cause of spinocerebellar ataxia type 5 (SCA5). The antibody is specific to SPTBN2.

实验方案

Product Specific Protocols
WB protocol for SPTBN2 antibody 55107-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
DrosophilaWB, IF

J Biol Chem

β-Spectrin regulates the Hippo signaling pathway and modulates the basal actin network.

Authors - Kenneth Kin Lam Wong
  • KD Validated
mouseWB

Front Mol Neurosci

Analyzing the mechanisms that facilitate the subtype-specific assembly of γ-aminobutyric acid type A receptors

Authors - Catherine Choi
mouseWB

Cerebellum

Nitric Oxide Critically Regulates Purkinje Neuron Dendritic Development Through a Metabotropic Glutamate Receptor Type 1-Mediated Mechanism.

Authors - Vasiliki Tellios
humanWB

Dis Markers

SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and Inhibiting Apoptosis

Authors - Xiaofen Zhou
humanWB

Exp Ther Med

Decreased SPTBN2 expression regulated by the ceRNA network is associated with poor prognosis and immune infiltration in low‑grade glioma

Authors - Guo-Rong Chen