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  • KD/KO Validated

SOD3 Polyclonal antibody

SOD3 Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (2)

Applications

WB, IP, ELISA

Conjugate

Unconjugated

Cat No : 14316-1-AP

Print datasheet

Synonyms

EC SOD, Extracellular superoxide dismutase, SOD3, Superoxide Dismutase 3



经过测试的应用

Positive WB detected inhuman urine sample, human heart tissue, human urine, human placenta tissue
Positive IP detected inhuman placenta tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

14316-1-AP targets SOD3 in WB, IP, ELISA applications and shows reactivity with human samples.

Tested Applications WB, IP, ELISA
Cited ApplicationsWB
Tested Reactivity human
Cited Reactivityhuman, mouse, rat
Immunogen SOD3 fusion protein Ag5556 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name superoxide dismutase 3, extracellular
Synonyms EC SOD, Extracellular superoxide dismutase, SOD3, Superoxide Dismutase 3
Calculated Molecular Weight 26 kDa
Observed Molecular Weight 25-33 kDa
GenBank Accession NumberBC014418
Gene Symbol SOD3
Gene ID (NCBI) 6649
RRIDAB_10898170
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP08294
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SOD is located intracellular (SOD-1; cytosolic, SOD-2; mitochondrial matrix) and extracellular (SOD-3), and catalyzes the dismutation of superoxide anion to H2O2. SOD3, or EC-SOD, is the most recently characterized SOD, exists as a copper and zinc-containing tetramer, and is synthesized containing a signal peptide that directs this enzyme exclusively to extracellular spaces. SOD-3 is a Mn-containing tetrameric protein with a subunit Mr of 24-35 kDa. The activity of EC-SOD is dependent on its ability to form a tetramer of 135 kDa.

实验方案

Product Specific Protocols
WB protocol for SOD3 antibody 14316-1-APDownload protocol
IP protocol for SOD3 antibody 14316-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouse,humanWB

Br J Pharmacol

Inhibition of DNA methylation derepresses PPARγ and attenuates pulmonary fibrosis.

Authors - Ai Wei
mouseWB

J Proteome Res

Sex-Specific Alterations in Placental Proteomics Induced by Intrauterine Hyperglycemia

Authors - Zhuo-Ran Ren
humanWB

Transl Pediatr

Identification and evaluation of fructose-bisphosphate aldolase B as a potential diagnostic biomarker in choledochal cysts patients: a quantitative proteomic analysis.

Authors - Gedong Ming
human,ratWB

Toxicol Appl Pharmacol

(-)-Epicatechin ameliorates cigarette smoke-induced lung inflammation via inhibiting ROS/NLRP3 inflammasome pathway in rats with COPD.

Authors - Xue Tian
humanWB

Clin Immunol

Oxidative stress is involved in immunosuppression and macrophage regulation in glioblastoma

Authors - Xisong Liang
  • KD Validated
mouseWB

Am J Transl Res

Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice

Authors - Wenci Weng