验证数据展示
经过测试的应用
| Positive WB detected in | HEK-293 cells, HEK-293, LNCaP, MG-63, U2OS cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
30497-1-AP targets SLX4IP in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag33034 Product name: Recombinant human SLX4IP protein Source: e coli.-derived, PGEX-4T Tag: GST Sequence: KLRRNALKEIVKRTETKSSVTSKSQTRRDTVETSSDSVIAEIARRRNDGQASSSPPSESMGQAKDSIKAAESHWGLPVQKLEKVNQTQPEDTSGQQKPHPGERLKTGLLSRSPVCSCESASPCPKQSPRVAKTQQKRRNCSSAEDFDHHGRVSLGSDRLVPREIIVEKSKAVRVLPASELSDPGLLLKQDLAKTTSKEELHVLESLSSRHLMKNNPGQAQQTGLATNTERLSTIQNSPTKKRKKYERGH 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | chromosome 20 open reading frame 94 |
| 别名 | C20orf94, bA204H22.1, bA254M13.1, UPF0492 protein C20orf94 |
| 计算分子量 | 46 kDa |
| 观测分子量 | 42 kDa |
| 基因名称 | C20orf94 |
| Gene ID (NCBI) | 128710 |
| RRID | AB_3742346 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q5VYV7 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SLX4IP is a nuclear adaptor protein that associates with the SLX4 DNA repair scaffold, contributing to DNA damage repair, replication stress responses, and telomere maintenance. By regulating nuclease-containing repair complexes and potentially supporting ALT-mediated telomere elongation, SLX4IP plays an important role in maintaining genomic stability. Dysregulation of SLX4IP has been implicated in cancer biology, particularly in tumors utilizing alternative telomere maintenance pathways.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for SLX4IP antibody 30497-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
