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验证数据展示

  • WB analysis of rat kidney using 88049-1-RR (same clone as 88049-1-PBS)

    WB analysis of rat kidney using 88049-1-RR (same clone as 88049-1-PBS)

    rat kidney tissue were subjected to SDS PAGE followed by western blot with 88049-1-RR (SLC6A8 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88049-1-PBS in a different storage buffer formulation.

  • WB analysis using 88049-1-RR (same clone as 88049-1-PBS)

    WB analysis using 88049-1-RR (same clone as 88049-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 88049-1-RR (SLC6A8 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88049-1-PBS in a different storage buffer formulation.

  • WB analysis using 88049-1-RR (same clone as 88049-1-PBS)

    WB analysis using 88049-1-RR (same clone as 88049-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 88049-1-RR (SLC6A8 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88049-1-PBS in a different storage buffer formulation.

SLC6A8 Recombinant monoclonal antibody, PBS Only

SLC6A8 Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 88049-1-PBS

产品说明书

CloneNo. 260302B8

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

Creatine transporter 1, CRT, CRTR, CT1, Sodium- and chloride-dependent creatine transporter 1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

88049-1-PBS targets SLC6A8 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag14500

Product name: Recombinant human SLC6A8 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 541-635 aa of BC012355

Sequence: YYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 solute carrier family 6 (neurotransmitter transporter, creatine), member 8
别名 Creatine transporter 1, CRT, CRTR, CT1, Sodium- and chloride-dependent creatine transporter 1
计算分子量 635 aa, 71 kDa
观测分子量 65-75 kDa
GenBank蛋白编号BC012355
基因名称 SLC6A8
Gene ID (NCBI) 6535
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP48029
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC6A8, also known as the sodium- and chloride-dependent creatine transporter 1 (CT1), plays a critical role in transporting creatine, a crucial molecule for energy metabolism, into cells. SLC6A8 belongs to the solute carrier family 6 (SLC6), responsible for transporting diverse molecules across cell membranes. SLC6A8 expression is highest in muscle, kidney, and other tissues with high energy demands. Mutations in SLC6A8 cause creatine transporter deficiency, an X-linked mental retardation disorder (PMID: 17465020). The 75 kDa band is a glycosylated modified form.

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