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验证数据展示

  • WB analysis using 83676-5-RR (same clone as 83676-5-PBS)

    WB analysis using 83676-5-RR (same clone as 83676-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83676-5-RR (SLC4A7/NBCn1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83676-5-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 83676-5-RR (same clone as 83676-5-PBS)

    WB analysis of HeLa using 83676-5-RR (same clone as 83676-5-PBS)

    WB result of SLC4A7/NBCn1 antibody (83676-5-RR; 1:6000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SLC4A7/NBCn1 transfected HeLa cells. This data was developed using the same antibody clone with 83676-5-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 83676-5-RR (same clone as 83676-5-PBS)

    WB analysis of HeLa using 83676-5-RR (same clone as 83676-5-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 83676-5-RR (SLC4A7/NBCn1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83676-5-PBS in a different storage buffer formulation.

SLC4A7/NBCn1 Recombinant monoclonal antibody, PBS Only

SLC4A7/NBCn1 Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 83676-5-PBS

产品说明书

CloneNo. 252520E8

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

NBCn1, SLC4A7, NBC2, NBC3

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy® SLC4A7/NBCn1 Ready-To-Use IHC Kit. SLC4A7/NBCn1 primary antibody included.

产品信息

83676-5-PBS targets SLC4A7/NBCn1 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 solute carrier family 4, sodium bicarbonate cotransporter, member 7
别名 NBCn1, SLC4A7, NBC2, NBC3
计算分子量 136 kDa
观测分子量 150-170 kDa
GenBank蛋白编号NM_003615
基因名称 NBCn1/SLC4A7
Gene ID (NCBI) 9497
RRIDAB_3743488
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9Y6M7
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SLC4A7 also known as NBCn1, NBC3, NBC2, is an electroneutral Na(+)/HCO(3)(-) cotransporter (PMID: 14736710). SLC4A7 mediates the coupled movement of sodium and bicarbonate ions across the plasma membrane. SLC4A7 plays a key role in macrophage acidification, mediating bicarbonate import into the cytoplasm which is crucial for net acid extrusion and maintenance of cytoplasmic pH during phagocytosis (PubMed:29779931). SLC4A7 is expressed in testis, spleen, and retina. SLC4A7 may be a major regulator of extracellular pH of retina where light stimulation produces an extracellular alkalization and may contribute as a solute transporter to the prevention of retinal detachment(PMID: 9610397). The molecular weight of SLC4A7/NBCn1 detected at 150-170 kDa may be due to glycosylation modification.

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