验证数据展示
产品信息
31031-1-PBS targets SLC46A3 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | IHC, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 |
CatNo: Ag34359 Product name: Recombinant human SLC46A3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 26-73 aa of BC060850 Sequence: QYVYRRIWEETGNYTFSSDSNISECEKNKSSPIFAFQEEVQKKVSRFN 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | solute carrier family 46, member 3 |
| 别名 | |
| 计算分子量 | 463 aa, 52 kDa |
| GenBank蛋白编号 | BC060850 |
| 基因名称 | SLC46A3 |
| Gene ID (NCBI) | 283537 |
| RRID | AB_3669822 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q7Z3Q1 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Solute carrier family 46 member 3 (SLC46A3) is a lysosomal membrane protein that belongs to the SLC46A family. SLC46A3 has been reported to be a proton-coupled, steroid conjugate, and bile acid transporter (PMID: 36741448). SLC46A3 plays an important role in Trastuzumab emtansine (T-DM1) treatment, a successful noncleavable antibody-drug conjugates (ADC) (PMID: 36741448).
