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SLC45A2 Polyclonal antibody

SLC45A2 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, ELISA and More (2)

Conjugate

Unconjugated

Cat No : 10453-1-AP

Print datasheet

Synonyms

1A1, AIM1, MATP, Melanoma antigen AIM1, Protein AIM 1, SHEP5, SLC45A2

验证数据展示

  • IHC staining of mouse colon using 10453-1-AP

    IHC staining of mouse colon using 10453-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 10453-1-AP (SLC45A2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human malignant melanoma using 10453-1-AP

    IHC staining of human malignant melanoma using 10453-1-AP

    Immunohistochemical analysis of paraffin-embedded human malignant melanoma tissue slide using 10453-1-AP (SLC45A2 Antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human malignant melanoma using 10453-1-AP

    IHC staining of human malignant melanoma using 10453-1-AP

    Immunohistochemical analysis of paraffin-embedded human malignant melanoma tissue slide using 10453-1-AP (SLC45A2 Antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of mouse colon using 10453-1-AP

    IHC staining of mouse colon using 10453-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 10453-1-AP (SLC45A2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

经过测试的应用

Positive IHC detected inmouse colon tissue, human malignant melanoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10453-1-AP targets SLC45A2 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IHC, ELISA
Cited ApplicationsWB, IF, IHC
Tested Reactivity human, mouse
Cited Reactivityhuman
Immunogen SLC45A2 fusion protein Ag0699 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name solute carrier family 45, member 2
Synonyms 1A1, AIM1, MATP, Melanoma antigen AIM1, Protein AIM 1, SHEP5, SLC45A2
Calculated Molecular Weight 58 kDa
Observed Molecular Weight 50-55 kDa
GenBank Accession NumberBC003597
Gene Symbol SLC45A2
Gene ID (NCBI) 51151
RRIDAB_2191075
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UMX9
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SLC45A2, also named as AIM1 and MATP, belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family. It is a melanocyte differentiation antigen. SLC45A2 may transport substances required for melanin biosynthesis. (PMID:17768386,21677667)Mutation of SLC45A2 cause oculocutaneous albinism type 4 (OCA4) which is disorder of pigmentation characterized by reduced biosynthesis of melanin in the skin, hair and eyes.

实验方案

Product Specific Protocols
IHC protocol for SLC45A2 antibody 10453-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB,IF

J Invest Dermatol

Homozygosity mapping and whole-exome sequencing to detect SLC45A2 and G6PC3 mutations in a single patient with oculocutaneous albinism and neutropenia.

Authors - Cullinane Andrew R AR
View Article
humanIHC

Front Oncol

New Prognostic Biomarkers and Drug Targets for Skin Cutaneous Melanoma via Comprehensive Bioinformatic Analysis and Validation.

Authors - Sitong Zhou
View Article