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验证数据展示

  • IHC staining of mouse colon using 10453-1-AP

    IHC staining of mouse colon using 10453-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 10453-1-AP (SLC45A2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human malignant melanoma using 10453-1-AP

    IHC staining of human malignant melanoma using 10453-1-AP

    Immunohistochemical analysis of paraffin-embedded human malignant melanoma tissue slide using 10453-1-AP (SLC45A2 Antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human malignant melanoma using 10453-1-AP

    IHC staining of human malignant melanoma using 10453-1-AP

    Immunohistochemical analysis of paraffin-embedded human malignant melanoma tissue slide using 10453-1-AP (SLC45A2 Antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of mouse colon using 10453-1-AP

    IHC staining of mouse colon using 10453-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 10453-1-AP (SLC45A2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

SLC45A2 Polyclonal antibody

SLC45A2 Polyclonal Antibody for IHC, ELISA
Cat No. 10453-1-AP

产品说明书

引用文献(2)

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, ELISA and More (2)

别名

1A1, AIM1, MATP, Melanoma antigen AIM1, Protein AIM 1, SHEP5, SLC45A2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive IHC detected inmouse colon tissue, human malignant melanoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10453-1-AP targets SLC45A2 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, ELISA Application Description
文献引用应用WB, IF, IHC
经测试反应性 human, mouse
文献引用反应性human
免疫原

CatNo: Ag0699

Product name: Recombinant human SLC45A2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-159 aa of BC003597

Sequence: MGSNSGQAGRHIYKSLADDGPFDSVEPPKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVLLSVGLPSSLYSIVWFLSPILGFLLQPVVGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIANPRRKLVWAISVTMIGVVLFDFAADFI

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 solute carrier family 45, member 2
别名 1A1, AIM1, MATP, Melanoma antigen AIM1, Protein AIM 1, SHEP5, SLC45A2
计算分子量 58 kDa
观测分子量 50-55 kDa
GenBank蛋白编号BC003597
基因名称 SLC45A2
Gene ID (NCBI) 51151
RRIDAB_2191075
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UMX9
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SLC45A2, also named as AIM1 and MATP, belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family. It is a melanocyte differentiation antigen. SLC45A2 may transport substances required for melanin biosynthesis. (PMID:17768386,21677667)Mutation of SLC45A2 cause oculocutaneous albinism type 4 (OCA4) which is disorder of pigmentation characterized by reduced biosynthesis of melanin in the skin, hair and eyes.

实验方案

Product Specific Protocols
IHC protocol for SLC45A2 antibody 10453-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB,IF

J Invest Dermatol

Homozygosity mapping and whole-exome sequencing to detect SLC45A2 and G6PC3 mutations in a single patient with oculocutaneous albinism and neutropenia.

Authors - Cullinane Andrew R AR
View Article
humanIHC

Front Oncol

New Prognostic Biomarkers and Drug Targets for Skin Cutaneous Melanoma via Comprehensive Bioinformatic Analysis and Validation.

Authors - Sitong Zhou
View Article