SLC36A4 Polyclonal antibody

SLC36A4 Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB,ELISA

Conjugate

Unconjugated

Cat No : 24066-1-AP

Print datasheet

Synonyms

PAT4, SLC36A4



经过测试的应用

Positive WB detected inA549 cells, HEK-293 cells, PC-3 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 24066-1-AP is SLC36A4 Fusion Protein expressed in E. coli.

Tested Applications WB,ELISA
Tested Reactivity human
Immunogen SLC36A4 fusion protein Ag21142 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name solute carrier family 36 (proton/amino acid symporter), member 4
Synonyms PAT4, SLC36A4
Calculated Molecular Weight 504 aa, 56 kDa
Observed Molecular Weight 41-66 kDa
GenBank Accession NumberBC047374
Gene Symbol SLC36A4
Gene ID (NCBI) 120103
RRIDAB_2879424
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
UNIPROT IDQ6YBV0
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SLC36A4 (also known as proton-coupled amino-acid transporter 4, PAT4), is a member of the solute carrier (SLC) 36 family which functions as transporter for amino acids and derivatives. SLC36A4 is widely distributed at the mRNA level in normal tissues and many cancer cell lines. It modulates the mTORC1 signaling and is essential for the proliferation of cancer cells. In addition, small GTPase Rab12 controls the degradation of SLC36A4, which indirectly modulates mTORC1 activity and autophagy. This antibody can recognize the endogenous SLC36A4 protein in multiple cell lines.

实验方案

Product Specific Protocols
WB protocol for SLC36A4 antibody 24066-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols