验证数据展示
产品信息
31429-1-PBS targets SLC2A4RG in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag35675 Product name: Recombinant human SLC2A4RG protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 200-350 aa of NM_020062.3 Sequence: FQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRIGVTL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | SLC2A4 regulator |
| 别名 | Huntington disease gene regulatory region-binding protein 1, HDBP-1, HDBP1, HDBP 1, GLUT4 enhancer factor |
| 计算分子量 | 41kDa，387aa |
| 观测分子量 | 30 kDa |
| GenBank蛋白编号 | NM_020062.3 |
| 基因名称 | SLC2A4RG |
| Gene ID (NCBI) | 56731 |
| RRID | AB_3742426 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q9NR83 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SLC2A4RG, or SLC2A4 Regulator, is a nuclear transcription factor that plays a role in activating the solute carrier family 2 member 4 gene, also known as GLUT4. SLC2A4RG has been implicated in the transcriptional regulation of genes, including its interaction with a 7-bp consensus sequence (GCCGGCG), which is an essential cis-regulatory element for Huntington's disease (HD) gene expression in neuronal cells. The SLC2A4RG protein is involved in the modulation of SLC2A4 expression and has been identified as a transcription factor that binds specifically to the promoter region of SLC2A4. It is also known to interact with another transcription factor, myocyte enhancer factor 2 (MEF2), to activate the transcription of SLC2A4. SLC2A4RG is expressed ubiquitously in various tissues, with higher expression levels observed in fat and kidney tissues.
