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验证数据展示

  • IHC staining of human colon cancer using 22711-1-AP

    IHC staining of human colon cancer using 22711-1-AP

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22711-1-AP (SLAMF6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • WB analysis using 22711-1-AP

    WB analysis using 22711-1-AP

    Daudi cells lysates were subjected to SDS PAGE followed by western blot with 22711-1-AP (NTB-A/SLAMF6 antibody) at a dilution of 1:4000, incubated at room temperature for 1.5 hours.

  • IHC staining of human tonsillitis using 22711-1-AP

    IHC staining of human tonsillitis using 22711-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22711-1-AP (NTB-A/SLAMF6 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human colon cancer using 22711-1-AP

    IHC staining of human colon cancer using 22711-1-AP

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22711-1-AP (SLAMF6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

NTB-A/SLAMF6 Polyclonal antibody

NTB-A/SLAMF6 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 22711-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, ELISA

别名

SLAMF6, Activating NK receptor, CD352, KALI, KALIb

缓冲液配方:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inDaudi cells
Positive IHC detected inhuman colon cancer tissue, human tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:8000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

22711-1-AP targets NTB-A/SLAMF6 in WB, IHC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag18517

Product name: Recombinant human SLAMF6 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 40-332 aa of BC114495

Sequence: LPLEFPAGEKVNFITWLFNETSLAFIVPHETKSPEIHVTNPKQGKRLNFTQSYSLQLSNLKMEDTGSYRAQISTKTSAKLSSYTLRILRQLRNIQVTNHSQLFQNMTCELHLTCSVEDADDNVSFRWEALGNTLSSQPNLTVSWDPRISSEQDYTCIAENAVSNLSFSVSAQKLCEDVKIQYTDTKMILFMVSGICIVFGFIILLLLVLRKRRDSLSLSTQRTQGPAESARNLEYVSVSPTNNTVYASVTHSNRETEIWTPRENDTITIYSTINHSKESKPTFSRATALDNVV

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 SLAM family member 6
别名 SLAMF6, Activating NK receptor, CD352, KALI, KALIb
计算分子量 332 aa, 37 kDa
观测分子量 60 kDa
GenBank蛋白编号BC114495
基因名称 SLAMF6
Gene ID (NCBI) 114836
RRIDAB_2879154
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96DU3
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Signaling lymphocyte activation molecule 6 (SLAMF6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules (PMID:31199820). SLAMF6 is a type I transmembrane protein with two extracellular immunoglobins (Ig)-like domains and three cytoplasmic tyrosine-based signaling motifs, one of which is immunoreceptor tyrosine-based switch motif (PMID:31315913). SLAMF6 is expressed on a wide variety of immune cells including T cells (also TFH), B cells, NK cells (expressed in humans only), double positive thymocytes, eosinophils, and neutrophils (mouse only) (PMID:11862385).

实验方案

Product Specific Protocols
IHC protocol for NTB-A/SLAMF6 antibody 22711-1-APDownload protocol
WB protocol for NTB-A/SLAMF6 antibody 22711-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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