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验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98101-1-RR (same clone as 98101-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98101-1-RR (same clone as 98101-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human SIRP Alpha/CD172a Rabbit Recombinant Antibody (98101-1-RR, Clone: 240789E1) or Isotype Control, and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98101-1-PBS in a different storage buffer formulation.

  • FC experiment of human peripheral blood leukocytes using 98101-1-RR (same clone as 98101-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98101-1-RR (same clone as 98101-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human SIRPA Rabbit Recombinant Antibody (98101-1-RR, Clone: 240789E1) (red) or Isotype Control (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98101-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98101-1-RR

    Affinity and Kinetic Characterization of 98101-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98101-1-RR against Human SIRP Alpha/CD172a were performed. The affinity constant is 3.39 nM.

Anti-Human SIRP Alpha/CD172a Rabbit Recombinant Antibody, PBS Only

SIRP Alpha/CD172a Uni-rAb® Recombinant Antibody for FC
Cat No. 98101-1-PBS

产品说明书

CloneNo. 240789E1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

SIRP Alpha, SIRPA, Inhibitory receptor SHPS-1, CD172a, CD172 antigen-like family member A

缓冲液配方:  PBS Only
PBS, Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

98101-1-PBS targets SIRP Alpha/CD172a in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原

Recombinant protein

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 signal-regulatory protein alpha
别名 SIRP Alpha, SIRPA, Inhibitory receptor SHPS-1, CD172a, CD172 antigen-like family member A
计算分子量55 kDa
GenBank蛋白编号NM_080792
基因名称 SIRP Alpha
Gene ID (NCBI) 140885
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDP78324
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SIRP Alpha, also known as CD172a, SHPS-1, and BIT, belongs to the SIRP family. SIRP Alpha is a transmembrane glycoprotein expressed explicitly on myeloid cells and provides a "do not eat me" signal after engaging with integrin-associated protein CD47 on tumor cells (PMID: 36419386). SIRP Alpha shows heterogeneity in molecular weight (~65-120 kDa) in various tissues due to differential glycosylation (PMID: 18051954).

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