验证数据展示
产品信息
55058-1-AP targets SHANK3 in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | SH3 and multiple ankyrin repeat domains 3 |
| 别名 | DEL22q13.3, KIAA1650, PROSAP2, PSAP2, sczd15, SHANK3, SPANK 2 |
| 计算分子量 | 186 kDa |
| GenBank蛋白编号 | NM_001080420 |
| 基因名称 | SHANK3 |
| Gene ID (NCBI) | 85358 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SHANK3, also named as KIAA1650 and PSAP2, seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. SHANK3 may play a role in the structural and functional organization of the dendritic spine and synaptic junction. The antibody is specific to SHANK3.