验证数据展示
产品信息
86842-1-PBS targets SHANK1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | SH3 and multiple ankyrin repeat domains 1 |
| 别名 | SHANK 1, Shank1a, Somatostatin receptor-interacting protein, SPANK 1, SPANK1 |
| 计算分子量 | 225 kDa |
| 观测分子量 | 159-225 kDa |
| GenBank蛋白编号 | NM_016148 |
| 基因名称 | SHANK1 |
| Gene ID (NCBI) | 50944 |
| RRID | AB_3745156 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9Y566 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SHANK1 belongs to the SHANK family. It seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. SHANK1 may play a role in the structural and functional organization of the dendritic spine and synaptic junction. The antibody is specific to SHANK1.
