SH3BP5 Monoclonal antibody, PBS Only

SH3BP5 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67841-1-PBS

产品说明书

CloneNo. 1B9D4

宿主/亚型

Mouse / IgG1

种属反应性

Human, rabbit, mouse, rat, pig, chicken

应用

WB, Indirect ELISA

SAB, SH3 domain binding protein 5, SH3BP 5, SH3BP5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

67841-1-PBS targets SH3BP5 in WB, Indirect ELISA applications and shows reactivity with Human, rabbit, mouse, rat, pig, chicken samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, rabbit, mouse, rat, pig, chicken
免疫原 SH3BP5 fusion protein Ag30252 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 SH3-domain binding protein 5 (BTK-associated)
别名 SAB, SH3 domain binding protein 5, SH3BP 5, SH3BP5
计算分子量 47 kDa
观测分子量75 kDa
GenBank蛋白编号BC010123
基因名称 SH3BP5
Gene ID (NCBI) 9467
RRIDAB_2918603
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO60239
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SH3BP5(SH3 domain-binding protein 5) is also named as SAB. It is previously isolated in a screen for proteins capable of binding to the Src homology 3 (SH3) domain of Bruton's tyrosine kinase (Btk) and could play a role in targeting JNK and Btk to mitochondria and/or mediating cross-talk between the JNK and Btk signalling pathways. It has 2 isoforms produced by alternative splicing with the molecular mass of 50 kDa and 32 kDa. There are two bands of 83 kDa and 70 kDa can be detected in A431 and the larger species may correspond to splice variants of SH3BP5 or SH3BP5 proteins that have undergone post-translational modification(PMID:12167088). In addition, we detect the band of 32 kDa as the isoform 2 of SH3BP5 and another band of 62 kDa besides the 47 kDa and 80 kDa.

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