SFRS6 Polyclonal antibody

SFRS6 Polyclonal Antibody for WB, ELISA
Cat No. 11772-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human and More (1)

应用

WB, ELISA

B52, Pre mRNA splicing factor SRP55, SFRS6, SRP55, SRSF6

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells, MCF-7 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 4 publications below

产品信息

11772-1-AP targets SFRS6 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB
经测试反应性 human
文献引用反应性human, mouse
免疫原 SFRS6 fusion protein Ag2412 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 splicing factor, arginine/serine-rich 6
别名 B52, Pre mRNA splicing factor SRP55, SFRS6, SRP55, SRSF6
计算分子量 344 aa, 40 kDa
观测分子量40 kDa
GenBank蛋白编号BC006832
基因名称 SFRS6
Gene ID (NCBI) 6431
RRIDAB_2185212
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ13247
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

SR proteins have a characteristic C-terminal Ser/Arg-rich repeat (RS domain) of variable length and constitute a family of highly conserved nuclear phosphoproteins that can function as both essential and alternative pre-mRNA splicing factors [PMID:7556075]. SRFS6 has a pivotal role in the TF exon 5 definition, an event essential for flTF biosynthesis. Besides, up- or down regulation of SRSF6 alters the splicing of several tumor suppressors and oncogenes to generate the oncogenic isoforms and reduce the tumor suppressive isoforms [PMID:23132731].

实验方案

Product Specific Protocols
WB protocol for SFRS6 antibody 11772-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Nat Commun

Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth.

Authors - Yuhan Chen
human,mouseWB

J Cell Mol Med

Renal Tubular Epithelial Cell-Derived hsa_circ_0008925 From Urine Is Related to Chronic Renal Fibrosis

Authors - Yuanhui Shi
mouseWB

Gene

Intron retention as a new pre-symptomatic marker of aging and its recovery to the normal state by a traditional Japanese multi-herbal medicine.

Authors - Norihiro Okada
mouseWB

Data Brief

Data of RNA-seq transcriptomes of liver, bone, heart, kidney and blood in klotho mice at a pre-symptomatic state and the effect of a traditional Japanese multi-herbal medicine, juzentaihoto.

Authors - Norihiro Okada
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