验证数据展示
发表文章中的应用
| WB | See 1 publications below |
| IP | See 1 publications below |
产品信息
10152-2-AP targets SFRS4 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IP |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse |
| 免疫原 |
CatNo: Ag0204 Product name: Recombinant human SFRS4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-180 aa of BC002781 Sequence: MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | splicing factor, arginine/serine-rich 4 |
| 别名 | Pre mRNA splicing factor SRP75, SFRS4, SRP001LB, SRP75, SRSF4 |
| 计算分子量 | 57 kDa |
| GenBank蛋白编号 | BC002781 |
| 基因名称 | SFRS4 |
| Gene ID (NCBI) | 6429 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q08170 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Splicing factor, arginine/serine-rich 4 (SFRS4, synonym: SRP75). SR proteins are a family of proteins that have a common epitope that binds active sites of polymerase II transcription. SRp75 protein, like other SR proteins, contains an N-terminal RNA recognition motif (RRM), a glycine-rich region, an internal region homologous to the RRM, and a long (315-amino-acid) C-terminal domain composed predominantly of alternating serine and arginine residues. Four of the other SR family members have been shown to restore activity to an otherwise splicing-deficient extract. SRp75 together with SRp20 can also complement the splicing-deficient extract. The apparent molecular mass of dephosphorylated SRp75 is 57 kDa.
发表文章
| Species | Application | Title |
|---|---|---|
J Virol Negative and positive mRNA splicing elements act competitively to regulate human immunodeficiency virus type 1 vif gene expression. | ||
PLoS One Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles. |
