SESN1 Recombinant antibody

SESN1 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 86008-1-RR

产品说明书

CloneNo. 250470G1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

EC:1.11.1.-, p53 regulated protein PA26, p53-regulated protein PA26, PA26, SEST1

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存


经过测试的应用

Positive WB detected inHEK-293 cells, K-562 cells, human skeletal muscle tissue, human testis tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:3000-1:30000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

86008-1-RR targets SESN1 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 SESN1 fusion protein Ag16462 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 sestrin 1
别名 EC:1.11.1.-, p53 regulated protein PA26, p53-regulated protein PA26, PA26, SEST1
计算分子量 551 aa, 64 kDa
观测分子量66 kDa
GenBank蛋白编号BC112036
基因名称 SESN1
Gene ID (NCBI) 27244
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9Y6P5
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Sestrins, including sestrin-1 (PA26), sestrin-2 (Hi95), and sestrin-3, are 48 to 65 kDa cystein sulfinyl reductases and they modulate peroxide signaling and antioxidant defense. These proteins selectively reduce or repair hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. Expression of these proteins is regulated by p53, a tumor suppressor protein. Sestrin 1 is implicated in the inhibition of cell growth. It is approximately a 66kDa protein in humans (551 amino acids).

实验方案

Product Specific Protocols
WB protocol for SESN1 antibody 86008-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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