验证数据展示
产品信息
67792-1-PBS targets SERBP1 in WB, IHC, IF-P, IP, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, pig, Canine samples.
经测试应用 | WB, IHC, IF-P, IP, Indirect ELISA Application Description |
经测试反应性 | Human, Mouse, Rat, pig, Canine |
免疫原 | SERBP1 fusion protein Ag30202 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | SERPINE1 mRNA binding protein 1 |
别名 | CGI 55, CHD3IP, DKFZp564M2423, FLJ90489, HABP4L, PAI RBP1, PAI1 RNA binding protein 1, PAIRBP1, SERBP1 |
计算分子量 | 45 kDa |
观测分子量 | 50 kDa |
GenBank蛋白编号 | BC008045 |
基因名称 | SERBP1 |
Gene ID (NCBI) | 26135 |
RRID | AB_2918556 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q8NC51 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The plasminogen activator system (PA) plays an important role in invasion and metastasis of solid tumors. The PA Inhibitor type 1 (PAI-1) is the main physiologic regulator of plasminogen activation. PAI-RBP1 (PAI-1 mRNA Binding Protein 1, also named SERBP1), is an RNA-binding protein containing an RG-rich domain and an RGG box domain that might be methylated by protein arginine N-methyltransferases (PRMTs). SERBP1 was identified as an interacting partner of a Tudor domain containing protein TDRD3, and can localize to cytoplasmic stress granules (SGs).