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验证数据展示

  • IHC staining of human colon cancer using 29191-1-AP (same clone as 29191-1-PBS)

    IHC staining of human colon cancer using 29191-1-AP (same clone as 29191-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 29191-1-AP (SEMA4B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29191-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 29191-1-AP (same clone as 29191-1-PBS)

    IHC staining of mouse brain using 29191-1-AP (same clone as 29191-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 29191-1-AP (SEMA4B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29191-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 29191-1-AP (same clone as 29191-1-PBS)

    IHC staining of human colon cancer using 29191-1-AP (same clone as 29191-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 29191-1-AP (SEMA4B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29191-1-PBS in a different storage buffer formulation.

SEMA4B Polyclonal antibody, PBS Only

SEMA4B Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 29191-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

KIAA1745, SEMAC, SemC

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

29191-1-PBS targets SEMA4B in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag30422

Product name: Recombinant human SEMA4B protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 92-256 aa of BC110853

Sequence: ALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFVASAYIPESLGSLQGD

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
别名 KIAA1745, SEMAC, SemC
GenBank蛋白编号BC110853
基因名称 SEMA4B
Gene ID (NCBI) 10509
RRIDAB_3086102
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NPR2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SEMA4B (Semaphorin 4B), belonging to the Class SEMA4, is a transmembrane homodimer glycoprotein. Lots of SEMA4 family members have been implicated in the formation and progression of tumors due to (PMID: 35676688). SEMA4B inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation (PMID: 25746385).

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