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验证数据展示

  • WB analysis using 27551-1-AP (same clone as 27551-1-PBS)

    WB analysis using 27551-1-AP (same clone as 27551-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27551-1-AP (SCN2A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27551-1-PBS in a different storage buffer formulation.

  • WB analysis using 27551-1-AP (same clone as 27551-1-PBS)

    WB analysis using 27551-1-AP (same clone as 27551-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27551-1-AP (SCN2A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27551-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 27551-1-AP (same clone as 27551-1-PBS)

    IF Staining of mouse brain using 27551-1-AP (same clone as 27551-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using SCN2A antibody (27551-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27551-1-PBS in a different storage buffer formulation.

SCN2A Polyclonal antibody, PBS Only

SCN2A Polyclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 27551-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF-P, Indirect ELISA

别名

BFIC3, HBA, HBSC II, HBSCI, HBSCII

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

27551-1-PBS targets SCN2A in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag26022

Product name: Recombinant human SCN2A protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 280-335 aa of NM_001040142

Sequence: MQWPPDNSSFEINITSFFNNSLDGNGTTFNRTVSIFNWDEYIEDKSHFYFLEGQNDA

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 sodium channel, voltage-gated, type II, alpha subunit
别名 BFIC3, HBA, HBSC II, HBSCI, HBSCII
计算分子量 228 kDa
观测分子量~250 kDa
GenBank蛋白编号NM_001040142
基因名称 SCN2A
Gene ID (NCBI) 6326
RRIDAB_3085969
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ99250
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The Sodium Channel, Voltage-Gated, Type II, Alpha (SCN2A) gene encodes the neuronal sodium channel NaV1.2. There are two major developmentally regulated splice isoforms of NaV1.2 that use mutually exclusive copies of the fifth coding exon and differ by one amino acid at position 209: Asparagine (Asn/N) vs. Aspartic acid (Asp/D). NaV1.2 is one of several sodium channels involved in initiation and propagation of action potentials in neurons. It's widely expressed throughout the human central nervous system, but not in peripheral tissues. (PMID: 29691040)

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