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验证数据展示

  • IHC staining of Human seminoma using 83039-7-RR (same clone as 83039-7-PBS)

    IHC staining of Human seminoma using 83039-7-RR (same clone as 83039-7-PBS)

    Immunohistochemical analysis of paraffin-embedded Human seminoma slide using 83039-7-RR (SALL4 antibody) at dilution of 1:3000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83039-7-PBS in a different storage buffer formulation.

  • IHC staining of Human seminoma using 83039-7-RR (same clone as 83039-7-PBS)

    IHC staining of Human seminoma using 83039-7-RR (same clone as 83039-7-PBS)

    Immunohistochemical analysis of paraffin-embedded Human seminoma slide using 83039-7-RR (SALL4 antibody) at dilution of 1:3000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83039-7-PBS in a different storage buffer formulation.

SALL4 Recombinant monoclonal antibody, PBS Only

SALL4 Uni-rAb® Recombinant Antibody for IHC, Indirect ELISA
Cat No. 83039-7-PBS

产品说明书

CloneNo. 230284F1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, Indirect ELISA

别名

DRRS, HSAL4, Sal like protein 4, Sal-like protein 4, Zinc finger protein 797

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

83039-7-PBS targets SALL4 in IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag16076

Product name: Recombinant human SALL4 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-350 aa of BC111714

Sequence: MSRRKQAKPQHINSEEDQGEQQPQQQTPEFADAAPAAPAAGELGAPVNHPGNDEVASEDEATVKRLRREETHVCEKCCAEFFSISEFLEHKKNCTKNPPVLIMNDSEGPVPSEDFSGAVLSHQPTSPGSKDCHRENGGSSEDMKEKPDAESVVYLKTETALPPTPQDISYLAKGKVANTNVTLQALRGTKVAVNQRSADALPAPVPGANSIPWVLEQILCLQQQQLQQIQLTEQIRIQVNMWASHALHSSGAGADTLKTLGSHMSQQVSAAVALLSQKAGSQGLSLDALKQAKLPHANIPSATSSLSPGLAPFTLKPDGTRVLPNVMSRLPSALLPQAPGSVLFQSPFST

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 sal-like 4 (Drosophila)
别名 DRRS, HSAL4, Sal like protein 4, Sal-like protein 4, Zinc finger protein 797
计算分子量 1053 aa, 112 kDa
GenBank蛋白编号BC111714
基因名称 SALL4
Gene ID (NCBI) 57167
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9UJQ4
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Sal-like protein 4 (SALL4), also named Zinc finger protein 797, contains 7 C2H2-type zinc fingers and belongs to the sal C2H2-type zinc-finger protein family. SALL4 is a transcription factor that exists in two splice isoforms and regulates transcription in embryonic stem cells, hematopoiesis, and acute myeloid leukemia. SALL4 is activated in fetal liver tissue, silenced in adult liver tissue, and reexpressed as an oncofetal protein in hepatocellular carcinoma (PMID: 26892498, 23758232). SALL4 has two isoforms with predicted molecular weights of 112 kDa (SALL4A) and 66 kDa (unmodified SALL4B), and SALL4B was found to be the dominant endogenous isoform in HCC cell lines. Ectopically expressed SALL4B migrated at 95 kDa modified by ubiquitination, 130 kDa modified by sumoylation (PMID: 23012367).

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