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Species Reactivity
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Species Reactivity
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Conjugate
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验证数据展示

  • WB analysis of K-562 using 66236-1-Ig (same clone as 66236-1-PBS)

    WB analysis of K-562 using 66236-1-Ig (same clone as 66236-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 66236-1-Ig (SALL4 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66236-1-PBS in a different storage buffer formulation.

SALL4 Monoclonal antibody, PBS Only

SALL4 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66236-1-PBS

产品说明书

CloneNo. 2B5B2

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, Indirect ELISA

别名

2B5B2, DRRS, HSAL4, Sal like protein 4, Sal-like protein 4

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

66236-1-PBS targets SALL4 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag17480

Product name: Recombinant human SALL4 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-350 aa of BC111714

Sequence: MSRRKQAKPQHINSEEDQGEQQPQQQTPEFADAAPAAPAAGELGAPVNHPGNDEVASEDEATVKRLRREETHVCEKCCAEFFSISEFLEHKKNCTKNPPVLIMNDSEGPVPSEDFSGAVLSHQPTSPGSKDCHRENGGSSEDMKEKPDAESVVYLKTETALPPTPQDISYLAKGKVANTNVTLQALRGTKVAVNQRSADALPAPVPGANSIPWVLEQILCLQQQQLQQIQLTEQIRIQVNMWASHALHSSGAGADTLKTLGSHMSQQVSAAVALLSQKAGSQGLSLDALKQAKLPHANIPSATSSLSPGLAPFTLKPDGTRVLPNVMSRLPSALLPQAPGSVLFQSPFST

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 sal-like 4 (Drosophila)
别名 2B5B2, DRRS, HSAL4, Sal like protein 4, Sal-like protein 4
计算分子量 1053 aa, 112 kDa
观测分子量 165 kDa
GenBank蛋白编号BC111714
基因名称 SALL4
Gene ID (NCBI) 57167
RRIDAB_2881625
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ9UJQ4
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SALL4, also named as Sal-like protein 4 or Zinc finger protein 797, Contains 7 C2H2-type zinc fingers and belongs to the sal C2H2-type zinc-finger protein family. SALL4 is constitutively expressed in acute myeloid leukemia. The constitutive expression of SALL4in mice is sufficient to induce MDS-like symptoms and transformation to AML that is transplantable. SALL4 is able to bind beta-catenin and activate the Wnt/beta-catenin signaling pathway. Sequence analysis of the larger cDNA fragment isolated revealed a single, large open-reading frame, designated as SALL4A, that started from a strong consensus initiation sequence and was expected to encode 1053 amino acids. The other splicing variant of SALL4, designated SALL4B, lacked the region corresponding to amino acids 385 to 820 of the full-length SALL4A. The putative protein encoded by SALL4B cDNA was expected to consist of 617 amino acids.