Recombinant Rat FSTL1 protein (rFc Tag)
种属
Rat
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 |
Not tested |
来源 | HEK293-derived Rat FSTL1 protein Glu19-Ile306 (Accession# Q62632) with a rabbit IgG Fc tag at the C-terminus. |
基因ID | 79210 |
蛋白编号 | Q62632 |
预测分子量 | 58.6 kDa |
SDS-PAGE | 60-80 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Follistatin-like 1 (FSTL1), initially discovered as a TGF-β1-induced gene, encodes a 308 amino acid secreted glycoprotein with a follistatin domain and two non-functional calcium-binding motifs. FSTL1 has been reported to be involved in the fate determination and maturation of epithelial cells. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure, demonstrating its functional importance. FSTL1 has been reported to exhibit both pro- and anti-inflammatory actions, with a specific anti-apoptotic and protective effect in cardiac or renal cell injury.
参考文献:
1.Mouillet JF, et al. (2015) Placenta.36(11):1231-8. 2.Murakami K, et al. (2012) FEBS Lett. 17;586(4):319-24. 3.Sylva M, et al. (2013) Birth Defects Res C Embryo Today.99(1):61-9. 4.Umezu T, et al. (2010) Proc Natl Acad Sci USA.107(10):4601-6.