Recombinant Rat FSTL1 protein (rFc Tag)

种属

Rat

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2605

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Synonyms

Follistatin-like protein 1, Follistatin-related protein 1, Frp, Fstl1



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Rat FSTL1 protein Glu19-Ile306 (Accession# Q62632) with a rabbit IgG Fc tag at the C-terminus.
基因ID 79210
蛋白编号 Q62632
预测分子量 58.6 kDa
SDS-PAGE 60-80 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Follistatin-like 1 (FSTL1), initially discovered as a TGF-β1-induced gene, encodes a 308 amino acid secreted glycoprotein with a follistatin domain and two non-functional calcium-binding motifs. FSTL1 has been reported to be involved in the fate determination and maturation of epithelial cells. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure, demonstrating its functional importance. FSTL1 has been reported to exhibit both pro- and anti-inflammatory actions, with a specific anti-apoptotic and protective effect in cardiac or renal cell injury.

参考文献:

1.Mouillet JF, et al. (2015) Placenta.36(11):1231-8. 2.Murakami K, et al. (2012) FEBS Lett. 17;586(4):319-24. 3.Sylva M, et al. (2013) Birth Defects Res C Embryo Today.99(1):61-9. 4.Umezu T, et al. (2010) Proc Natl Acad Sci USA.107(10):4601-6.