Recombinant Rat CXCL7 protein (mFc Tag)
种属
Rat
纯度
>90 %, SDS-PAGE
标签
mFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Rat CXCL7 protein Ile46-Ile107 (Accession# A6KKE5) with a mouse IgG Fc tag at the N-terminus. |
| 基因ID | 246358 |
| 蛋白编号 | A6KKE5 |
| 预测分子量 | 34.5 kDa |
| SDS-PAGE | 34-37 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CXCL7 is a platelet-derived growth factor that belongs to the CXC chemokine family, functioning as a potent chemo-attractant and activator of neutrophils through binding to its receptor CXCR2. CXCL7 has been demonstrated to participate in a variety of cellular processes, such as DNA synthesis, glycolysis, mitosis, intracellular cAMP accumulation, prostaglandin E2 secretion, as well as the synthesis of hyaluronic acid and plasminogen activator. In cancer cells, CXCL7 exerts promotion of cancer development in a variety of different cancer types, including renal cell carcinoma, lung cancer, and breast cancer.
参考文献:
1.Yu M, et al. (2010) J Oncol. 2010:939407. 2.Guo Q, et al. (2017) Oncol Rep. 37(2):1114-1122. 3.Kinouchi T, et al. (2017) Cancer Sci. 108(12):2495-2502. 4.Wang YH, et al. (2021) Cell Death Dis. 12(12):1090.
