验证数据展示
产品信息
Biotin-17781 targets RSPO2 in applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag11216 Product name: Recombinant human RSPO2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-214 aa of BC027938 Sequence: SRASYVSNPICKGCLSCSKDNGCSRCQQKLFFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETMECVEGCEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIVKKPVKDTIPCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLATDRANQ 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | R-spondin 2 homolog (Xenopus laevis) |
| 别名 | CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 |
| 计算分子量 | 243 aa, 28 kDa |
| 观测分子量 | 33 kDa |
| GenBank蛋白编号 | BC027938 |
| 基因名称 | RSPO2 |
| Gene ID (NCBI) | 340419 |
| RRID | AB_2883059 |
| 偶联类型 | Biotin |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q6UXX9 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
RSPO2 is one of the R-spondins (RSPOs) which comprise a family of four secreted proteins that have important roles in cell proliferation, cell fate determination and organogenesis. RSPOs typically exert their effects by potentiating the Wnt/beta-catenin signaling pathway. Overexpression of Rspo2 is sufficient to promote bone morphogenetic protein-induced mineralization Rspo2 was identified as a novel common integration site (CIS) for the mouse mammary tumor virus (MMTV) in viral induced mouse mammary tumors.
