验证数据展示
产品信息
Biotin-17781 targets RSPO2 in applications and shows reactivity with human, mouse, rat samples.
经测试应用 | Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | RSPO2 fusion protein Ag11216 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | R-spondin 2 homolog (Xenopus laevis) |
别名 | CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 |
计算分子量 | 243 aa, 28 kDa |
观测分子量 | 33 kDa |
GenBank蛋白编号 | BC027938 |
基因名称 | RSPO2 |
Gene ID (NCBI) | 340419 |
RRID | AB_2883059 |
偶联类型 | Biotin |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q6UXX9 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
RSPO2 is one of the R-spondins (RSPOs) which comprise a family of four secreted proteins that have important roles in cell proliferation, cell fate determination and organogenesis. RSPOs typically exert their effects by potentiating the Wnt/beta-catenin signaling pathway. Overexpression of Rspo2 is sufficient to promote bone morphogenetic protein-induced mineralization Rspo2 was identified as a novel common integration site (CIS) for the mouse mammary tumor virus (MMTV) in viral induced mouse mammary tumors.