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验证数据展示

  • IP experiment of Ramos using 12396-1-AP (same clone as 12396-1-PBS)

    IP experiment of Ramos using 12396-1-AP (same clone as 12396-1-PBS)

    IP result of anti-RGS13 (IP:12396-1-AP, 4ug; Detection:12396-1-AP 1:500) with Ramos cells lysate 1680 ug. This data was developed using the same antibody clone with 12396-1-PBS in a different storage buffer formulation.

  • IHC staining of human lymphoma using 12396-1-AP (same clone as 12396-1-PBS)

    IHC staining of human lymphoma using 12396-1-AP (same clone as 12396-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 12396-1-AP (RGS13 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12396-1-PBS in a different storage buffer formulation.

RGS13 Polyclonal antibody, PBS Only

RGS13 Polyclonal Antibody for IHC, IP, Indirect ELISA
Cat No. 12396-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, IP, Indirect ELISA

别名

Regulator of G-protein signaling 13

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

12396-1-PBS targets RGS13 in IHC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag3077

Product name: Recombinant human RGS13 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-159 aa of BC016667

Sequence: MSRRNCWICKMCRDESKRPPSNLTLEEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKIASRWSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRFLKSEMYQKLLKTMQSNNSF

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 regulator of G-protein signaling 13
别名 Regulator of G-protein signaling 13
计算分子量 159 aa, 19 kDa
观测分子量 17-19 kDa
GenBank蛋白编号BC016667
基因名称 RGS13
Gene ID (NCBI) 6003
RRIDAB_3741827
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO14921
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Regulator of G-protein signaling 13 (RGS13) is an R4 subfamily member that attenuates both Gαi and Gαq-dependent signaling including chemokine reponses in B cells (PMID: 11875076, PMID: 12193720). RGS13 interacted with both Gialpha and Gqalpha and strongly impaired signaling through G(i)-linked signaling pathways, including signaling through the chemokine receptors CXCR4 and CXCR5 (PMID: 12193720). Human mast cells express multiple RGS proteins, of which RGS13 is among the most abundant (PMID: 19017978).

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