×
Use Able AI chat for product recommendations

验证数据展示

  • IF Staining of mouse brain using 20689-1-AP (same clone as 20689-1-PBS)

    IF Staining of mouse brain using 20689-1-AP (same clone as 20689-1-PBS)

    Dual immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using 20689-1-AP (RELN antibody) at dilution of 1:50 and 66564-1-Ig (Tbr1 antibody), further stained with Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) for 20689-1-AP and Alexa Fluor 594-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) for 66564-1-Ig. This data was developed using the same antibody clone with 20689-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 20689-1-AP (same clone as 20689-1-PBS)

    IHC staining of human liver cancer using 20689-1-AP (same clone as 20689-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 20689-1-AP (RELN antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20689-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver cancer using 20689-1-AP (same clone as 20689-1-PBS)

    IHC staining of human liver cancer using 20689-1-AP (same clone as 20689-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 20689-1-AP (RELN antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20689-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 20689-1-AP (same clone as 20689-1-PBS)

    IF Staining of mouse brain using 20689-1-AP (same clone as 20689-1-PBS)

    Dual immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using 20689-1-AP (RELN antibody) at dilution of 1:50 and 66564-1-Ig (Tbr1 antibody), further stained with Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) for 20689-1-AP and Alexa Fluor 594-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L) for 66564-1-Ig. This data was developed using the same antibody clone with 20689-1-PBS in a different storage buffer formulation.

RELN Polyclonal antibody, PBS Only

RELN Polyclonal Antibody for IHC, IF-P, Indirect ELISA
Cat No. 20689-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, IF-P, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

20689-1-PBS targets RELN in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 reelin
别名
计算分子量 388 kDa
GenBank蛋白编号NM_005045
基因名称 RELN
Gene ID (NCBI) 5649
RRIDAB_2878724
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP78509
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RELN belongs to the reelin family. It is an extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. It is a secreted glycoprotein which is essential for neuronal migration in the cortex. RELN regulates microtubule function in neurons and neuronal migration. It affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and ApoER2, RELN induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation. Defects in RELN are the cause of lissencephaly type 2 (LIS2).

||
New chat

Able™

正在加载，请稍候...